Bibliografía seleccionada

D. E. Ayala, R. C. Hermida, A. Mojón, and J. R. Fernández, Cardiovascular risk of resistant hypertension: dependence on treatment-time regimen of blood pressure-lowering medications, Chronobiol Int, vol. 30, pp. 340–52, Mar 2013.
doi: 10.3109/07420528.2012.701455.

N. P. Bowles, S. S. Thosar, M. X. Herzig, and S. A. Shea, Chronotherapy for hypertension, Curr Hypertens Rep, vol. 20, p. 97, 09 2018.
doi: 10.1007/s11906-018-0897-4.

J. J. Crespo, L. Piñeiro, A. Otero, C. Castiñeira, M. T. Ríos, A. Regueiro, A. Mojón, S. Lorenzo, D. E. Ayala, R. C. Hermida, and Hygia Project Investigators, Administration-time-dependent effects of hypertension treatment on ambulatory blood pressure in patients with chronic kidney disease, Chronobiol Int, vol. 30, pp. 159–75, Mar 2013.
doi: 10.3109/07420528.2012.701459.

R. C. Hermida, C. Calvo, D. E. Ayala, M. J. Domínguez, M. Covelo, J. R. Fernández, A. Mojón, and J. E. López, Administration time-dependent effects of valsartan on ambulatory blood pressure in hypertensive subjects, Hypertension, vol. 42, pp. 283–90, Sep 2003.
doi: 10.1161/01.HYP.0000084855.32823.DA.

R. C. Hermida, D. E. Ayala, C. Calvo, J. E. López, J. R. Fernández, A. Mojón, M. J. Domínguez, and M. Covelo, Administration time-dependent effects of aspirin on blood pressure in untreated hypertensive patients, Hypertension, vol. 41, pp. 1259–67, Jun 2003.
doi: 10.1161/01.HYP.0000072335.73748.0D.

R. C. Hermida, C. Calvo, D. E. Ayala, and J. E. López, Decrease in urinary albumin excretion associated with the normalization of nocturnal blood pressure in hypertensive subjects, Hypertension, vol. 46, pp. 960–8, Oct 2005.
doi: 10.1161/01.HYP.0000174616.36290.fa.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Influence of circadian time of hypertension treatment on cardiovascular risk: results of the mapec study, Chronobiol Int, vol. 27, pp. 1629–51, Sep 2010.
doi: 10.3109/07420528.2010.510230.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Influence of time of day of blood pressure-lowering treatment on cardiovascular risk in hypertensive patients with type 2 diabetes, Diabetes Care, vol. 34, pp. 1270–6, Jun 2011.
doi: 10.2337/dc11-0297.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Bedtime dosing of antihypertensive medications reduces cardiovascular risk in ckd, J Am Soc Nephrol, vol. 22, pp. 2313–21, Dec 2011.
doi: 10.1681/ASN.2011040361.

R. C. Hermida, D. E. Ayala, J. R. Fernández, A. Mojón, M. H. Smolensky, F. Fabbian, and F. Portaluppi, Administration-time differences in effects of hypertension medications on ambulatory blood pressure regulation, Chronobiol Int, vol. 30, pp. 280–314, Mar 2013.
doi: 10.3109/07420528.2012.709448.

R. C. Hermida, D. E. Ayala, M. H. Smolensky, J. R. Fernández, A. Mojón, and F. Portaluppi, Chronotherapy with conventional blood pressure medications improves management of hypertension and reduces cardiovascular and stroke risks, Hypertens Res, vol. 39, pp. 277–92, May 2016.
doi: 10.1038/hr.2015.142.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes: a randomised controlled trial, Diabetologia, vol. 59, pp. 255–65, Feb 2016.
doi: 10.1007/s00125-015-3749-7.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Risk of incident chronic kidney disease is better reduced by bedtime than upon-awakening ingestion of hypertension medications, Hypertens Res, vol. 41, pp. 342–353, May 2018.
doi: 10.1038/s41440-018-0029-1.

F. Portaluppi, R. Tiseo, M. H. Smolensky, R. C. Hermida, D. E. Ayala, and F. Fabbian, Circadian rhythms and cardiovascular health, Sleep Med Rev, vol. 16, pp. 151–66, Apr 2012.
doi: 10.1016/j.smrv.2011.04.003.

G. C. Roush, J. Fapohunda, and J. B. Kostis, Evening dosing of antihypertensive therapy to reduce cardiovascular events: a third type of evidence based on a systematic review and meta-analysis of randomized trials, J Clin Hypertens (Greenwich), vol. 16, pp. 561–8, Aug 2014.
doi: 10.1111/jch.12354.

R. C. Hermida, J. J. Crespo, M. Domínguez-Sardiña, A. Otero, A. Moyá, M. T. Ríos, E. Sineiro, M. C. Castiñeira, P. A. Callejas, L. Pousa, J. L. Salgado, C. Durán, J. J. Sánchez, J. R. Fernández, A. Mojón, D. E. Ayala, and H. P. Investigators, Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial, Eur Heart J, Oct 2019.
doi: 10.1093/eurheartj/ehz754.

R. C. Hermida, M. H. Smolensky, D. E. Ayala, F. Portaluppi, J. J. Crespo, F. Fabbian, E. Haus, R. Manfredini, A. Mojón, A. Moyá, L. Piñeiro, M. T. Ríos, A. Otero, H. Balan, and J. R. Fernández, Recomendaciones 2013 para el uso de la monitorización ambulatoria de la presión arterial para el diagnóstico de hipertensión en adultos, valoración de riesgo cardiovascular y obtención de objetivos terapéuticos (resumen). recomendaciones conjuntas de la international society for chronobiology (isc), american association of medical chronobiology and chronotherapeutics (aamcc), sociedad española de cronobiología aplicada, cronoterapia y riesgo vascular (secac), sociedad española de arteriosclerosis (sea) y romanian society of internal medicine (rsim), Clin Investig Arterioscler, vol. 25, no. 2, pp. 74–82, 2013.
doi: 10.1016/j.arteri.2013.03.002.

R. C. Hermida, M. H. Smolensky, D. E. Ayala, F. Portaluppi, J. J. Crespo, F. Fabbian, E. Haus, R. Manfredini, A. Mojón, A. Moyá, L. Piñeiro, M. T. Ríos, A. Otero, H. Balan, and J. R. Fernández, 2013 ambulatory blood pressure monitoring recommendations for the diagnosis of adult hypertension, assessment of cardiovascular and other hypertension-associated risk, and attainment of therapeutic goals, Chronobiol Int, vol. 30, pp. 355–410, Apr 2013.
doi: 10.3109/07420528.2013.750490.

R. C. Hermida, M. H. Smolensky, D. E. Ayala, and F. Portaluppi, Ambulatory blood pressure monitoring (abpm) as the reference standard for diagnosis of hypertension and assessment of vascular risk in adults, Chronobiol Int, vol. 32, no. 10, pp. 1329–42, 2015.
doi: 10.3109/07420528.2015.1113804.

M. A. Piper, C. V. Evans, B. U. Burda, K. L. Margolis, E. O’Connor, and E. P. Whitlock, Diagnostic and predictive accuracy of blood pressure screening methods with consideration of rescreening intervals: a systematic review for the u.s. preventive services task force, Ann Intern Med, vol. 162, pp. 192–204, Feb 2015.
doi: 10.7326/M14-1539.

M. H. Smolensky, D. E. Ayala, and R. C. Hermida, Ambulatory blood pressure monitoring (abpm) as THE reference standard to confirm diagnosis of hypertension in adults: Recommendation of the 2015 u.s. preventive services task force (uspstf), Chronobiol Int, vol. 32, no. 9, pp. 1320–2, 2015.
doi: 10.3109/07420528.2015.1082106.

D. E. Ayala, A. Moyá, J. J. Crespo, C. Castiñeira, M. Domínguez-Sardiña, S. Gomara, E. Sineiro, A. Mojón, M. J. Fontao, R. C. Hermida, and Hygia Project Investigators, Circadian pattern of ambulatory blood pressure in hypertensive patients with and without type 2 diabetes, Chronobiol Int, vol. 30, pp. 99–115, Mar 2013.
doi: 10.3109/07420528.2012.701489.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Sleep-time blood pressure as a therapeutic target for cardiovascular risk reduction in type 2 diabetes, Am J Hypertens, vol. 25, pp. 325–34, Mar 2012.
doi: 10.1038/ajh.2011.231.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Ambulatory blood pressure thresholds for diagnosis of hypertension in patients with and without type 2 diabetes based on cardiovascular outcomes, Chronobiol Int, vol. 30, pp. 132–44, Mar 2013.
doi: 10.3109/07420528.2012.702584.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Sleep-time bp: prognostic marker of type 2 diabetes and therapeutic target for prevention, Diabetologia, vol. 59, pp. 244–54, Feb 2016.
doi: 10.1007/s00125-015-3748-8.

A. Moyá, J. J. Crespo, D. E. Ayala, M. T. Ríos, L. Pousa, P. A. Callejas, J. L. Salgado, A. Mojón, J. R. Fernández, R. C. Hermida, and Hygia Project Investigators, Effects of time-of-day of hypertension treatment on ambulatory blood pressure and clinical characteristics of patients with type 2 diabetes, Chronobiol Int, vol. 30, pp. 116–31, Mar 2013.
doi: 10.3109/07420528.2012.702587.

D. E. Ayala and R. C. Hermida, Ambulatory blood pressure monitoring for the early identification of hypertension in pregnancy, Chronobiol Int, vol. 30, pp. 233–59, Mar 2013.
doi: 10.3109/07420528.2012.714687.

D. E. Ayala, R. Ucieda, and R. C. Hermida, Chronotherapy with low-dose aspirin for prevention of complications in pregnancy, Chronobiol Int, vol. 30, pp. 260–79, Mar 2013.
doi: 10.3109/07420528.2012.717455.

R. C. Hermida, D. E. Ayala, M. H. Smolensky, A. Mojón, J. R. Fernández, J. J. Crespo, A. Moyá, M. T. Ríos, and F. Portaluppi, Chronotherapy improves blood pressure control and reduces vascular risk in ckd, Nat Rev Nephrol, vol. 9, pp. 358–68, Jun 2013.
doi: 10.1038/nrneph.2013.79.

R. C. Hermida, M. H. Smolensky, D. E. Ayala, J. R. Fernández, A. Moyá, J. J. Crespo, A. Mojón, M. T. Ríos, F. Fabbian, and F. Portaluppi, Abnormalities in chronic kidney disease of ambulatory blood pressure 24 h patterning and normalization by bedtime hypertension chronotherapy, Nephrol Dial Transplant, vol. 29, pp. 1160–7, Jun 2014.
doi: 10.1093/ndt/gft285.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Sleep-time ambulatory bp is an independent prognostic marker of ckd, J Am Soc Nephrol, vol. 28, pp. 2802–2811, Sep 2017.
doi: 10.1681/ASN.2016111186.

A. Mojón, D. E. Ayala, L. Piñeiro, A. Otero, J. J. Crespo, A. Moyá, J. Bóveda, J. P. de Lis, J. R. Fernández, R. C. Hermida, and Hygia Project Investigators, Comparison of ambulatory blood pressure parameters of hypertensive patients with and without chronic kidney disease, Chronobiol Int, vol. 30, pp. 145–58, Mar 2013.
doi: 10.3109/07420528.2012.703083.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Decreasing sleep-time blood pressure determined by ambulatory monitoring reduces cardiovascular risk, J Am Coll Cardiol, vol. 58, pp. 1165–73, Sep 2011.
doi: 10.1016/j.jacc.2011.04.043.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Sleep-time blood pressure and the prognostic value of isolated-office and masked hypertension, Am J Hypertens, vol. 25, pp. 297–305, Mar 2012.
doi: 10.1038/ajh.2011.208.

R. C. Hermida, D. E. Ayala, M. J. Fontao, A. Mojón, and J. R. Fernández, Ambulatory blood pressure monitoring: importance of sampling rate and duration–48 versus 24 hours–on the accurate assessment of cardiovascular risk, Chronobiol Int, vol. 30, pp. 55–67, Mar 2013.
doi: 10.3109/07420528.2012.701457.

R. C. Hermida, D. E. Ayala, A. Mojón, and J. R. Fernández, Blunted sleep-time relative blood pressure decline increases cardiovascular risk independent of blood pressure level–the "normotensive non-dipper" paradox, Chronobiol Int, vol. 30, pp. 87–98, Mar 2013.
doi: 10.3109/07420528.2012.701127.

R. C. Hermida, D. E. Ayala, A. Mojón, M. J. Fontao, L. Chayán, and J. R. Fernández, Differences between men and women in ambulatory blood pressure thresholds for diagnosis of hypertension based on cardiovascular outcomes, Chronobiol Int, vol. 30, pp. 221–32, Mar 2013.
doi: 10.3109/07420528.2012.701487.

R. C. Hermida, D. E. Ayala, M. T. Ríos, J. R. Fernández, A. Mojón, and M. H. Smolensky, Around-the-clock ambulatory blood pressure monitoring is required to properly diagnose resistant hypertension and assess associated vascular risk, Curr Hypertens Rep, vol. 16, p. 445, Jul 2014.
doi: 10.1007/s11906-014-0445-9.

R. C. Hermida, D. E. Ayala, M. H. Smolensky, J. R. Fernández, A. Mojón, and F. Portaluppi, Sleep-time blood pressure: Unique sensitive prognostic marker of vascular risk and therapeutic target for prevention, Sleep Med Rev, vol. 33, pp. 17–27, 06 2017.
doi: 10.1016/j.smrv.2016.04.001.

R. C. Hermida, J. J. Crespo, A. Otero, M. Domínguez-Sardiña, A. Moyá, M. T. Ríos, M. C. Castiñeira, P. A. Callejas, L. Pousa, E. Sineiro, J. L. Salgado, C. Durán, J. J. Sánchez, J. R. Fernández, A. Mojón, D. E. Ayala, and Hygia Project Investigators, Asleep blood pressure: significant prognostic marker of vascular risk and therapeutic target for prevention, Eur Heart J, vol. 39, pp. 4159–4171, 12 2018.
doi: 10.1093/eurheartj/ehy475.

R. C. Hermida, D. E. Ayala, J. R. Fernández, A. Mojón, and M. H. Smolensky, Hypertension: New perspective on its definition and clinical management by bedtime therapy substantially reduces cardiovascular disease risk, Eur J Clin Invest, vol. 48, p. e12909, May 2018.
doi: 10.1111/eci.12909.

R. C. Hermida, D. E. Ayala, A. Mojón, M. H. Smolensky, and J. R. Fernández, Diagnosis and management of hypertension: around-the-clock ambulatory blood pressure monitoring is substantially more effective and less costly than daytime office blood pressure measurements, Chronobiol Int, vol. 36, pp. 1515–1527, Nov 2019.
doi: 10.1080/07420528.2019.1658201.